Nkhani Zanyama: Kupita patsogolo mu Avian Truvenza

Nkhani 01

Kuzindikira koyamba kwa H4n6 ya avian fuluwenza mu Maback a Mallard (Anas Playrhynchnos) ku Israeli

Avishai Lublin, nikki thirie, Irina Shoda, ABIAN Simoda, Gila, Wayne Harnous, a Rurine LA

PMID: 3568756; Doi :.111111 / TBED.14610

Avian fuluwenza fuluus fulus (Aiv) amawopseza kwambiri thanzi la nyama komanso anthu padziko lonse lapansi. Monga momwe madzi akutchire amatumiza IIV padziko lonse lapansi, kufufuza kuchuluka kwa Aiv m'matumbo ndikofunikira kuti kumvetsetsa kufalikira ndi kufalikira kwa matenda a nyama ndi anthu. Mu kafukufukuyu, H4n6 Subtype Aiv adatalikirana nthawi yoyamba kuchoka pa zitsanzo za a Faecal ya abakha obiriwira (Anas Playrhynos) ku Israeli. Zotsatira za phylogenetic za Ha ndi na majini akuwonetsa kuti kupsinjika kumeneku kumakhala kofanana kwambiri ndi ku European komanso kulonyera. Monga momwe Israeli ilili m'njira ya Arctic ku Arctic ku Arctic-African, amaganiziridwa kuti zovuta zake zidayambitsidwa ndi mbalame zosamukira. Kusanthula kwa phylogenetic kwa majini amkati (pb1, pb2, pb2, pa, n sp, ndikuwonetsa kuti chochita china chobwezera cham'mbuyomu chidachitika kale. Subppype iyi ya Aiv ili ndi ndalama zambiri zobwezeretsa, zimatha kupatsira nkhumba zotayidwa ndi kumanga zolandila zaumunthu, ndipo zingayambitse matenda azoonotioti mtsogolo.

News 02

Chidule cha mafille avian fuluwenza mu EU, March-June 2022

Ulamuliro wa ku Europe wa Zakudya za ku Europe, European Center kwa matenda kupewa matenda ndi kuwongolera, labouni ya European Union of Avian fuluwenza

PMID: 35949938; PMC93567711; Doi :.2903 / J.EFSA.20215.7415

Mu 2021-2022, matenda a pathogenic avian (HPAI) anali mliri waukulu kwambiri ku Europe, ndi anthu 2,398 omwe akuwaza m'maiko 36 m'Yuniani. Pakati pa 16 Marichi ndi 10 June 2022, mayiko 28 eu / EEA. Munthawi yomwe mukuwunikanso, 86% yakufalikira nkhuku idachitika chifukwa cha kufala kwa HPPIIV, ndikulemba kwa France kwa 68% yazomwe zimachitika pazaka zonse za m'ma 24%. Germany inali ndi chiwerengero chachikulu kwambiri cha mikangano yamtchire (Milandu ya 158), yotsatiridwa ndi Netherlands (98 milandu) ndi UK (milandu 48).

Zotsatira za Kusanthula kwa majini akuwonetsa kuti HPAPIV pano ya HPAIV ku Europe ndi ya Spectrum 2.3.4 b. Kuyambira lipoti lomaliza, anayi a H5N6, awiri a H9n2 ndi matenda awiri a H3N8 adanenedwa ku China ndipo matenda a anthu a H5N1 adanenedwa ku USA. Chiwopsezo chotenga kachilomboka chidayesedwa kuti anthu onse azikhala otsika komanso ochepa kuti athe kupezeka kuti ali mu EU / EEA.

 Nkhani 03

Masinthidwe atsalira 127, 183 ndipo 212 pa mtundu wa ha amakhudza

Antigeniccity, Kubwereza ndi Pathogenicity ya H9n2 Avian fuluwenza

Fanlu fan,Bing Liang,Yongzhen Zhao,Yaping zhang,Qingzheng liu,Miao Tian,Yiqng zheng,Huizhi Xa,Yasuo Suzuki,Hualan Chen,Jihui ping

PMID: 34724348; Doi :.11111 / TBED.14363

B9N2 Subtype of Avian fuluwenza fuluwer (Aiv) ndi imodzi mwazipatso zazikulu zomwe zikukhudza thanzi la bizinesi ya nkhuku. Mu phunziroli, mavuto awiri a H9n2 Subtype AIV wokhala ndi chibadwa chofananira koma kutsutsana kosiyanasiyana, dzina / js / 2018 (JS / 2018), anali otalikirana ndi famu ya nkhuku. Kusanthula kotsatira kunawonetsa kuti JS / 75 ndi js / 76 amasiyana mu Amino Amiyo Adidi Okhazikika (127, 183 ndi 212) of haemagglutinin (haemaglitin (haemaglinin (haemaglutinin. Kuti muwone kusiyana kwa zinthu zachilengedwe pakati pa js / 75 ndi js / 76, ma virus asanu ndi amodzi omwe amapangidwa pogwiritsa ntchito njira yosinthira ma genetic / 8/1934 (pr8) ngati tcheni chachikulu. Zambiri kuchokera ku mayesedwe a nkhuku ndi mayeso a Hi adawonetsa kuti R-76 / pr8 adayendetsa kuthawa kwa antigenic kwambiri chifukwa cha Amino Acids paudindo pa 127 ndi 183 mu gene. Kafukufuku wowonjezera adatsimikiza kuti glycosyty pamalo a 127n adachitika mu JS / 76 ndi osintha. Kulandila madera omangirizawo kunawonetsa kuti ma virus onse oyambiranso, kupatula wosowa kwambiri, wosatsutsika wopanda pake, womangidwa mosavuta. Kukula ndi mbewa za mbewa kumawonetsa kuti kachilombo ka Hycosy-Gycosy-glycosy kunayambitsa pang'ono m'maselo a A549 ndipo anali ochepa kwambiri mu mbewa poyerekeza ndi kachilombo ka virus. Chifukwa chake, glycosylation ndi amino acids mu gene wa ha imayambitsa kusiyana pakati pa kugwiritsidwa ntchito kwa mankhwalawa a 2 h9n2.

Source: China chanyama ndi Epidemiology Center