Matenda achangu a m'magazi

Matendawa amatulutsa (BSI) amatanthauza kuyankha kwadongosolo syndrome yoyambitsidwa ndi kuluka kwa microgenic microgenic ndi poizoni m'magazi.

Njira ya matendawa imadziwika ndi kutsegula ndikumasulidwa kwa oimba ofalitsa otupa, ndikupangitsa kuti kutentha thupi lalitali, kuzizira, komanso kusokonekera, kuchepa, komanso kuchuluka kwa anthu ambiri. zopezeka ndi sepsis ndi septic shack milandu, ikuwerengera zaka 40% ndipo pafupifupi 20% ya ICU yomwe yapezedwa milandu. Ndipo zimalumikizidwa kwambiri ndi vuto lalikulu la vuto, makamaka popanda ma antimicrobial mankhwala ndi kuwongolera matenda.

Kugawika kwa matenda a magazi molingana ndi kuchuluka kwa matenda

Nkhuku

Kukhalapo kwa mabakiteriya kapena bowa m'magazi.

Septicemia

Matenda azachipatala chifukwa cha kuwukira kwa mabakiteriya a pathogenic ndi poizoni m'magazi, ndi matenda oopsa.

Pyohemia

Kuopsezedwa kwa moyo komwe kumachitika chifukwa cha kusamalira thupi kwa thupi chifukwa cha matenda.

Chodetsa nkhawa kwambiri ndi matenda awiri otsatirawa.

Matenda apadera a Catheter

Matendawa amagwirizanitsidwa ndi ma cathester omwe amakhazikitsidwa m'mapiri amitundu (mwachitsanzo, ma catheral otupitsa amphaka apakati, zovala za catherous, zojambula, zotupa za dialysis, etc.).

Chithandizo Chapadera cha Endocarditis

Ndi matenda opatsirana chifukwa cha kusamuka kwa matenda a endocardium ndi mavesi amtima, ndipo amadziwika ndi mapangidwe a zinthu zosafunikira m'makulidwe monga mawonekedwe a metastasis kapena sepsant chilombo chokhetsa.

Matenda a Matenda a Magazi:

Matendawa amadziwika kuti ndi wodwala chikhalidwe chabwino cha magazi ndi zizindikiro za matenda adongosolo. Matendawa amatha kukhala achiwiri kwa masamba ena omwe amadwala matenda monga matenda am'mapapu, m'mimba m'mimba, kapena matenda oyamba. Zanenedwa kuti 40% ya odwala ndi sepsis kapena kugwedezeka kwa septic kumachitika chifukwa cha matenda a magazi [4]. Akuti milandu 47-50 miliyoni ya sepsis imachitika padziko lonse lapansi chaka chilichonse, zimayambitsa kufa pafupifupi miliyoni miliyoni, ndipo pafupifupi pafupifupi kufa pafupifupi 1 masekondi asanu ndi atatu.

Njira zodziwira matenda a m'magazi

01 PCT

Ngati dongosolo laukadaulo ndi kutupa masentimita, chiphunzitso cha calcitoninogen chimawonjezera mwachangu pansi pa kunyengerera kwa bakiteriya, ndipo mulingo wa chiwonetsero cha seramu chikuwonetsa mkhalidwe woopsa wa matendawa ndipo ndi chizindikiro chabwino cha matendawa.

Maselo 0.2 ndi zinthu zotsatsa

Mamolekyu a cell ashesk (cam) amatenga nawo mbali mu njira zingapo za phynopathology, monga kuyankha komanso kutupa komanso kuchita mbali yofunika kwambiri. Izi zikuphatikiza Il-6, Il-8, TNF-A, VCAM-1, etc.

03 Endotoxin, G yeniyeni

Mabakiteriya osokoneza magazini olowera magazi kuti atulutse endotoxin amatha kuyambitsa Endotoxemia; .

04 mabology biology

DNA kapena RNA yotulutsidwa m'magazi ndi tizilombo tating'onoting'ono timayesedwa, kapena pambuyo pa chikhalidwe cha magazi.

Chikhalidwe cha Magazi 05

Mabakiteriya kapena bowa m'makhalidwe amwazi ndi "muyezo wa golide".

Chikhalidwe cha magazi ndi chimodzi mwazinthu zosavuta kwambiri, zomwe zimagwiritsidwa ntchito kwambiri komanso zogwiritsidwa ntchito kwambiri kuti tidziwe matendawa ndipo ndi gawo la matenda otsimikizira kuti magazi m'thupi. Kuzindikira kwachikhalidwe koyambirira kwa magazi ndi antimicrobial mankhwala oyambirira komanso oyenera antimicy ndi njira zazikulu zomwe ziyenera kutengedwa kuti zithetse matenda a magazi.

Chikhalidwe cha Magazi ndi muyeso wa golide wopezeka ndi matenda magazi, omwe amatha kusiyanitsa matenda a pathogen, kuphatikiza ndi chizindikiritso cha zotsatira zamankhwala ndikupereka chikonzero cholondola komanso cholondola. Komabe, vuto la nthawi yayitali lopereka lipoti lakhala likukhudza matenda komanso chithandizo chamankhwala chomwe anthu ambiri samachiritsidwa ndi maantibayotiki a nthawi yake komanso ogwira ntchito nthawi yayitali.

Chifukwa chake, chikhalidwe chamagazi ndi chizindikiritso cha matenda omwe ali ndi matenda omwe amawakayikira amagwiritsa ntchito mafotokozedwe ang'onoang'ono) Lipoti loyambirira liyenera kunenedwa kuchipatala mkati mwa 1 h ya lipoti lazikhalidwe labwino; Lipoti la Tertiary likuyenera kukwaniritsidwa posachedwa (nthawi zambiri mkati mwa 48-72 H pa mabakiteriya) kutengera vuto la labotale.